Maintaining end stage kidney disease patients on regular hemodialysis is usually associated with many acute complications
Acute complications during hemodialysis
Maintaining
end stage kidney disease patients on regular hemodialysis is usually associated
with many acute complications. They include hypotension (low blood pressure),
cramps, nausea and vomiting, headache, acute chest pain, low back pain, pruritus
(itching), pyrexia (fever) and chills. The underlying mechanisms of these
events that occur during dialysis are not clearly recognized.
Causes
With
prolonged time of the dialysis session or an increased amount of fluid removal
(called ultrafiltration), certain acute complications will emerge, such as
headache, nausea, and vomiting will be more frequent within dialysis session. A
new patient who started dialysis for the first time may develop certain
syndrome called “disequilibrium syndrome” that occur due to rapid removal of
the uremic toxins (toxins of renal failure). A variant related to this syndrome
may explain the aforementioned complications, particularly so in non-compliant or
poorly dialyzed patients who are amenable for aggressive courses of intense
dialysis.
CHEST PAIN
The
occurrence of chest pain during the dialysis session may be attributed to either
hypotension (low blood pressure) or to an underlying disequilibrium syndrome
(see above). Other possible causes may include angina pectoris, hemolytic
events, and the rare air embolism (air inside blood vessel). Moreover, despite pulmonary
embolism is a very rare event in patients on dialysis, this event may be observed
with manipulation of a thrombus (clot) inside a vessel or if the patient’s
dialysis access has been occluded. Management of chest pain during dialysis
depends to a great extent on its impact on patient’s circulation, if the
patient is hemodynamically unstable or has a positive history of ischemic heart
disease or via clinical examination, return of blood and cessation of dialysis
session may allow better management. Acutely, the decision to continue or stop
the dialysis treatment because of chest pain is based upon clinical findings,
such as hemodynamic stability, and the results of the history and physical
examination.
Angina Pectoris
In
view of the increased incidence of ischemic heart disease in dialysis patients,
any chest discomfort should be dealt seriously as an anginal pain related to an
ischemic heart background. A full detailed history, complete physical examination,
an ECG (electrocardiogram) as well as lab testing for cardiac enzymes (e.g. cardiac
troponin) may help to settle a diagnosis. If the patient still on dialysis,
oxygen therapy, chewing of aspirin, decline of the pump speed (blood pump),
reduction of the net ultrafiltration (fluid removal) and analgesic administration
with rapid forms of nitrates may be individualized accordingly. Preventive
measures of this complication may include prophylactic administration of
nitrates and/or beta blocking agents with enough time. These agents should be
given cautiously to dialysis patient, as lowering of blood pressure
(hypotension) is a common association. The latter, however, may impede extra
fluid removal during dialysis, a vital target of commencing dialysis therapy.
Dyspnea (shortness of breath)
Volume
overload is one of the commonest causes of dyspnea in dialysis patient
particularly in anuric patients (No urine), where extracellular fluid can be accumulated
rapidly. Other causes of dyspnea among dialysis patients may include current medications,
cardiac causes, underlying infection, allergy related to first-use dialyzer or
medications, as well as hematological diseases such as heparin (anticoagulant
agent)-related thrombocytopenia should be considered.
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